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Reference \ Pharmacology

Table of Contents


1. Structure-Activity Relationships in Percutaneous Absorption
     Jurij J. Hostynek

2. Methods for In Vitro Percutaneous Absorption
     Robert L. Bronaugh

3. Percutaneous Absorption in Humans
     Ronald C. Wester and Howard I. Maibach

4. Percutaneous Absorption of Hazardous Substances from Soil and Water
     Ronald C. Wester and Howard I. Maibach

5. Isolated Perfused Porcine Skin Flap
     Jim E. Riviere

6. Methods in Physiologically Based Pharmacokinetic Modeling
     James N. McDougal

7. Methods for In Vitro Metabolism Studies
     Robert L. Bronaugh

8. Developing a Toxicology Evaluation Plan for Transdermal Delivery Systems
     Mary E. Prevo, Michel Cormier and James Matriano

9. Animal, Human and In Vitro Test Methods for Predicting Skin Irritation
     Sunita M. Patil, Esther Patrick and Howard I. Maibach

10. Structure-Activity Relationships in Contrast Sensitisation: Classification and Ranking of Allergens
     Jurij J. Hostynek

11. Test Methods for Allergic Contact Dermatitis in Animals
     Georg Klecak

12. The Local Lymph Node Assay
     Ian Kimber

13. Test Methods for Allergic Contact Dermatitis in Humans
     Francis N. Marzulli and Howard I. Maibach

14. Contact Urticaria Syndrome
     Smita Amin, Arto Lahti and Howard I. Maibach

15. Diagnostic Tests in Dermatotoxicology
     Smita Amin, Antii I. Laurerma and Howard I. Maibach

16. Uses of Cytokines in Dermatotoxicology
     G. Frank Gerberick, Elizabeth E. Sikorski, Cindy A. Ryan and Laura C. Limardi

17. Characterisation of Epidermal Langerhans Cells
     Marie Cumberbatch, Rebecca J. Dearman and Ian Kimber

18. Measuring and Quantifying Ultraviolet Radiation Exposures
     David H. Sliney

19. Animal Models for Phototoxicity Testing
     Lark A. Lambert, Wayne G. Warner and Andrija Kornhauser

20. Photoirritation (Phototoxicity) Testing in Humans
     Francis N. Marzulli and Howard I. Maibach

21. The Evaluation of Photoallergic Contact Sensitisers in Humans
     Kays Kaidbey

22. Chemical Leukoderma (Depigmentation)
     Howard I. Maibach, Jorge R. Toro, Gerald A. Gellin and Leslie P. McCarty

23. New Models to Assess In Vitro Action of Retinoids
     Serge Michel and Braham Shroot

24. Sample Protocols for Carcinogenesis and Protocarcinogenesis
     P. Donald Forbes, Christopher P. Sambuco, George E. Dearlove, Robert M. Partker, Anthony L. Kiorpes and John H. Wedig

25. Testing for Reproductive Hazards from Dermal Exposure
     Thomas F.X. Collins


26. Quantitative Sensory Testing
     Gil Yosipovitch and David Yarnitsky


27. Alternative Methods in Dermatotoxicology
     Mary A. Perkins, Michael K. Robinson and Rosemarie Osborne


28. Skin Equivalents to Measure Phototoxicity
     Andre Rougier, Catherine Cohen and Roland Roguet

29. A Practical Process for Assesing the Validity of Alternative Methods for Toxicity Testing
     Leon H. Bruner, Gregory J. Carr, Mark Chamberlain and Rodger D. Curren

30. Update on Agency Initiatives in Alternative Methods
     Sidney Green
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