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| Reference \ Pigmented Lesions | Table of Contents
| Section I: Introduction and Historical Perspective
1. Introduction 2.Historical Perspective
Section II: Basic Biology of the Pigment Cell System and Causation of Melanoma 3. Basic Biology 4. Skin Immunity and Melanoma Development 5. Environmental Influences on Cutaneous Melanoma Development 6. Racial Predispositions and Genetics of Melanoma
Section III: Epidemiology, Prevention and Screening
7. Epidemiology of Cutaneous Melanoma, Incidence Worldwide, Current Trends 8. Prevention Strategies, early Diagnosis and Results of Education Campaigns 9. The Role of Sunscreens in Prevention 10. Screening for Cutaneous melanoma
Section IV: Histopathology and Classification
11. Histological Diagnosis and Classification of Cutaneous Melanoma 12. Pathological Reporting of Cutaneous Melanoma 13. Immunohistochemistry and Special Diagnostic Techniques 14. Ultrastaging
Section V: Staging and Prognosis
15. Staging System for Cutaneous Melanoma 16. Prognosis and Factors Affecting Prognosis of Cutaneous Melanoma
Section VI: Diagnosis of Primary Cutaneous Melanoma and Initial Investigations
17. Precursor Lesions - Recognition and Management 18. Clinical Presentation and Diagnosis 19. Surface Microscopy Features of Melanoma 20. Computer Assisted/Automated Diagnosis of Melanoma 21. Initial Staging Investigations
Section VII: Diagnosis of Primary Cutaneous Melanoma Site
22. Excision of Melanoma Site, Excision Margins 23. Reconstruction After Wide Excision
Section VIII: Management of Regional Lymph Nodes
24. Elective Lymph Node Dissection 25. Site-Specific Techniques (a) Axillary Dissection (b) Groin and Pelvic Dissection (c) Neck Dissection and Parotidectomy 26. Sentinel Lymph Node Biopsy (a) The Concept (b) Historical Aspects (c) Identification with Blue Dye and Gamma Probe (d) Lymphoscintigraphy (e) Results to Date (f) Unresolved Questions
Section IX: Special Situations
27. Melanoma in Childhood 28. Desmoplastic and Neurotropic Melanoma
Section X: Management of Locally and Locoregionally Recurrent Melanoma
29. Role of Post-Operative Radiotherapy 30. Isolated Limb Perfusion - Technical Aspects 31. Isolated Limb Perfusion - Results and Complications 32. Isolated Limb Infusion 33. Preclinical Studies and Future Directions 34. Other Treatments
Section XI: Diagnosis and Local Management of Systemic Metastatic Disease
35. Follow-up 36. Diagnosis of Systemic Metastatic Disease (a) General Principles (b) Conventional Imaging Techniques (c) PET Scanning (d) Blood Tests and Markers 37. Local Treatment of Systemic Melanoma Metastases (a) Principles (b) Lung Metastases (c) Hepatic (d) Gastrointestinal and Other Intraabdominal Metastases (e) Brain Metastases 38. Role of Radiotherapy in Metastatic Melanoma - Overview
Section XII: Systemic Therapy for Melanoma
39. Management of Patient with Advanced Disease 40. Adjuvant Chemotherapy and Chemo-biotherapy for High Risk Primary Disease and Resected Metastatic Melanoma 41. Principles of Immunotherapy for Melanoma 42. Adjuvant Immunotherapy for High Risk Primary Disease and Resected Metastatic Melanoma 43. Systemic Chemotherapy and Chemo-biotherapy for Non-Resected Metastatic Melanoma 44. Immunotherapy for Non-Resected Metastatic Melanoma 45. Gene Therapy 46. New Approaches to the Management of Disseminated Disease
Section XIII: Primary Melanomas in Non-Cutaneous Sites
47. Mucosal and Glans Penis Melanomas 48. Primary Lung Melanomas 49. Primary Melanomas of the Gastrointestinal Tract 50. Ocular melanomas
Section XIV: Towards Improved Melanoma Management
51. Guidelines for the Management of Melanoma
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