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Reference \ Pigmented Lesions

Table of Contents


Section I: Introduction and Historical Perspective

1. Introduction
2.Historical Perspective

Section II: Basic Biology of the Pigment Cell System and Causation of Melanoma

3. Basic Biology
4. Skin Immunity and Melanoma Development
5. Environmental Influences on Cutaneous Melanoma Development
6. Racial Predispositions and Genetics of Melanoma

Section III: Epidemiology, Prevention and Screening

7. Epidemiology of Cutaneous Melanoma, Incidence Worldwide, Current Trends
8. Prevention Strategies, early Diagnosis and Results of Education Campaigns
9. The Role of Sunscreens in Prevention
10. Screening for Cutaneous melanoma

Section IV: Histopathology and Classification

11. Histological Diagnosis and Classification of Cutaneous Melanoma
12. Pathological Reporting of Cutaneous Melanoma
13. Immunohistochemistry and Special Diagnostic Techniques
14. Ultrastaging

Section V: Staging and Prognosis

15. Staging System for Cutaneous Melanoma
16. Prognosis and Factors Affecting Prognosis of Cutaneous Melanoma

Section VI: Diagnosis of Primary Cutaneous Melanoma and Initial Investigations

17. Precursor Lesions - Recognition and Management
18. Clinical Presentation and Diagnosis
19. Surface Microscopy Features of Melanoma
20. Computer Assisted/Automated Diagnosis of Melanoma
21. Initial Staging Investigations

Section VII: Diagnosis of Primary Cutaneous Melanoma Site

22. Excision of Melanoma Site, Excision Margins
23. Reconstruction After Wide Excision

Section VIII: Management of Regional Lymph Nodes

24. Elective Lymph Node Dissection
25. Site-Specific Techniques
    (a) Axillary Dissection
    (b) Groin and Pelvic Dissection
    (c) Neck Dissection and Parotidectomy
26. Sentinel Lymph Node Biopsy
    (a) The Concept
    (b) Historical Aspects
    (c) Identification with Blue Dye and Gamma Probe
    (d) Lymphoscintigraphy
    (e) Results to Date
    (f) Unresolved Questions

Section IX: Special Situations

27. Melanoma in Childhood
28. Desmoplastic and Neurotropic Melanoma

Section X: Management of Locally and Locoregionally Recurrent Melanoma

29. Role of Post-Operative Radiotherapy
30. Isolated Limb Perfusion - Technical Aspects
31. Isolated Limb Perfusion - Results and Complications
32. Isolated Limb Infusion
33. Preclinical Studies and Future Directions
34. Other Treatments

Section XI: Diagnosis and Local Management of Systemic Metastatic Disease

35. Follow-up
36. Diagnosis of Systemic Metastatic Disease
    (a) General Principles
    (b) Conventional Imaging Techniques
    (c) PET Scanning
    (d) Blood Tests and Markers
37. Local Treatment of Systemic Melanoma Metastases
    (a) Principles
    (b) Lung Metastases
    (c) Hepatic
    (d) Gastrointestinal and Other Intraabdominal Metastases
    (e) Brain Metastases
38. Role of Radiotherapy in Metastatic Melanoma - Overview

Section XII: Systemic Therapy for Melanoma

39. Management of Patient with Advanced Disease
40. Adjuvant Chemotherapy and Chemo-biotherapy for High Risk Primary Disease and Resected Metastatic Melanoma
41. Principles of Immunotherapy for Melanoma
42. Adjuvant Immunotherapy for High Risk Primary Disease and Resected Metastatic Melanoma
43. Systemic Chemotherapy and Chemo-biotherapy for Non-Resected Metastatic Melanoma
44. Immunotherapy for Non-Resected Metastatic Melanoma
45. Gene Therapy
46. New Approaches to the Management of Disseminated Disease

Section XIII: Primary Melanomas in Non-Cutaneous Sites

47. Mucosal and Glans Penis Melanomas
48. Primary Lung Melanomas
49. Primary Melanomas of the Gastrointestinal Tract
50. Ocular melanomas

Section XIV: Towards Improved Melanoma Management

51. Guidelines for the Management of Melanoma
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