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| Reference \ Symptoms & Signs |
Table of Contents
| PART I. Clinical Classification of Itch
Definitions of Itch
Gil Yosipovitch and Malcolm W. Greaves
PART II. Basic Mechanisms of Itch
Neurophysiologic Basis of Itch
Martin Schmelz and Hermann O. Handwerker
Pain and Itch
Martin Schmelz and Hermann O. Handwerker
Central Neural Mechanisms of Itch
David Andrew and A. D. Craig
Animal Models of Itch: Scratching Away at the Problem
Earl Carstens and Yasushi Kuraishi
Histamine-Induced Discriminative and Affective Responses Revealed by Functional MRI
Francis McGlone, Roman Rukwied, Matt Howard, and David Hitchcock
Central Nervous System Imaging of Itch with PET
Ulf Darsow, Alexander Drzezga, and Johannes Ring
Skin Nerve Anatomy: Neuropeptide Distribution and Its Relationship to Itch
Dieter Metze
Substance P and Itch
Tsugunobu Andoh and Yasushi Kuraishi
Peripheral Opiate Receptor System in Human Epidermis and Itch
Paul Lorenz Bigliardi and Mei Bigliardi-Qi
Antipruritic Activity of a Novel k-Opioid Receptor Agonist, TRK-820
Jun Utsumi, Yuko Togashi, Hideo Umeuchi, Kiyoshi Okano, Toshiaki Tanaka, and Hiroshi Nagase
Putative Role of Cannabinoids in Experimentally Induced Itch and Inflammation in Human Skin
Roman Rukwied, Melita Dvorak, Allan Watkinson, and Francis McGlone
Itch Models in Animals, with Special Emphasis on the Serotonin Model in Rats
Jens Schiersing Thomsen
Human Itch Models, with Special Emphasis on Itch in SLS-Inflamed and Normal Skin
Jens Schiersing Thomsen
PART III. Evaluation of Patients with Itch
Microdialysis in Itch Research
Martin Schmelz
Measuring Nocturnal Scratching in Atopic Dermatitits
Toshiya Ebata
Itch Questionnaires as Tools for Itch Evaluation
Gil Yosipovitch
PART IV. Epidemiology and Characteristics of Itch
Epidemiology of Itching in Skin and Systemic Diseases
Gil Yosipovitch
Uremic Pruritus: New Perspectives and Insights from Recent Trials
Thomas Mettang, Dominik Mark Alscher, and Christiane Pauli-Magnus
Pruritus Complicating Liver Disease
Nora V. Bergasa and E. Anthony Jones
Itch in HIV-Infected Patients
Maria I. Duque, Gil Yosipovitch, and P. Samuel Pegram
Neuropathic Pruritis
Gil Yosipovitch, Rashel Goodkin, Ellen Mary Wingard, and Jeffrey D. Bernhard
Clinical Features of Itch in Atopic Eczema
Ulf Darsow and Johannes Ring
Postburn Itch
Robert D. Nelson
Pruritus in Lichen Simplex Chronicus and Lichen Amyloidosis
Yung-Hian Leow and Gil Yosipovitch
PART V. Treatment of Itch
Treatment of Pruritus in Internal and Dermatological Diseases with Opioid Receptor Antagonists
Sonja Ständer and Dieter Metze
Prospects for a Novel K-Opioid Receptor Agonist, TRK-820, in Uremic Pruritus
Hiroo Kumagai, Shigeaki Matsukawa, Jun Utsumi, and Takao Saruta
Treatment of Pruritic Skin Diseases with Topical Capsaicin
Sonja Ständer and Dieter Metze
Mechanistic and Clinical Assessment of Zangrad®, an Extract of the Amazonian Ethnomedicine Sangre de Grado, for the Treatment of Itch
Mark J. S. Miller, Brian K. Reuter, John L. Wallace, Keith A. Sharkey, and Paul Bobrowski
Reduction in Itch Severity with Topical Immunomodulators: A New Approach for Patients with Inflammatory Disease
Alan B. Fleischer, Jr.
5-HT3 Receptor Antagonists as Antipruritics
Elke Weisshaar
Cutaneous Nerve Stimulation in the Treatment of Localized Itch
Joanna Wallengren
PART VI. Social and Psychological Aspects
Psychosomatic Aspects of Pruritus
Uwe Gieler, Volker Niemeier, Burkhard Brosig, and Jörg Kupfer
On Psychological Factors Affecting Reports of Itch Perception
Elia E. Psouni
Itching as a Focus of Mental Disturbance
Yuval Melamed and Gil Yosipovitch
Index
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